Tumor-suppressive disruption of cancer subtype-associated super enhancer circuits by small molecule treatment

Transcriptional cancer subtypes which correlate with traits such as tumor growth, drug sensitivity or the chances of relapse and metastasis, have been described for several malignancies. The core regulatory circuits (CRCs) defining these subtypes are established by chromatin super enhancers (SEs) dr...

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Detalles Bibliográficos
Autores principales: Koeniger, Anke, Polo, Pierfrancesco, Brichkina, Anna, Finkernagel, Florian, Visekruna, Alexander, Nist, Andrea, Stiewe, Thorsten, Daude, Michael, Diederich, Wibke E, Gress, Thomas M, Adhikary, Till, Lauth, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900422/
https://www.ncbi.nlm.nih.gov/pubmed/36755960
http://dx.doi.org/10.1093/narcan/zcad007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900422/
https://www.ncbi.nlm.nih.gov/pubmed/36755960
http://dx.doi.org/10.1093/narcan/zcad007

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