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SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc

Disruption of the blood-spinal cord barrier (BSCB) leads to inflammatory cell infiltration and neural cell death, thus, contributing to poor functional recovery after spinal cord injury (SCI). Previous studies have suggested that Sirtuin 1 (SIRT1), an NAD(+)-dependent class III histone deacetylase,...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Qin, Tao, Gao, Peng, Tao, Zhiwen, Wang, Xiaowei, Wu, Mengyuan, Gu, Jun, Chu, Bo, Zheng, Ziyang, Yi, Jiang, Xu, Tao, Huang, Yifan, Liu, Hao, Zhao, Shujie, Ren, Yongxin, Chen, Jian, Yin, Guoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900454/
https://www.ncbi.nlm.nih.gov/pubmed/36716673
http://dx.doi.org/10.1016/j.redox.2023.102615