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SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc
Disruption of the blood-spinal cord barrier (BSCB) leads to inflammatory cell infiltration and neural cell death, thus, contributing to poor functional recovery after spinal cord injury (SCI). Previous studies have suggested that Sirtuin 1 (SIRT1), an NAD(+)-dependent class III histone deacetylase,...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900454/ https://www.ncbi.nlm.nih.gov/pubmed/36716673 http://dx.doi.org/10.1016/j.redox.2023.102615 |