Measurement of FGFR3 signaling at the cell membrane via total internal reflection fluorescence microscopy to compare the activation of FGFR3 mutants

Fibroblast growth factor receptors (FGFRs) initiate signal transduction via the RAS/mitogen-activated protein kinase pathway by their tyrosine kinase activation known to determine cell growth, tissue differentiation, and apoptosis. Recently, many missense mutations have been reported for FGFR3, but...

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Detalles Bibliográficos
Autores principales: Hartl, Ingrid, Brumovska, Veronika, Striedner, Yasmin, Yasari, Atena, Schütz, Gerhard J., Sevcsik, Eva, Tiemann-Boege, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900515/
https://www.ncbi.nlm.nih.gov/pubmed/36581204
http://dx.doi.org/10.1016/j.jbc.2022.102832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900515/
https://www.ncbi.nlm.nih.gov/pubmed/36581204
http://dx.doi.org/10.1016/j.jbc.2022.102832

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