αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b

CD1 glycoproteins present lipid-based antigens to T-cell receptors (TCRs). A role for CD1b in T-cell–mediated autoreactivity was proposed when it was established that CD1b can present self-phospholipids with short alkyl chains (∼C34) to T cells; however, the structural characteristics of this presen...

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Detalles Bibliográficos
Autores principales: Farquhar, Rachel, Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie, Shahine, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900620/
https://www.ncbi.nlm.nih.gov/pubmed/36587766
http://dx.doi.org/10.1016/j.jbc.2022.102849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900620/
https://www.ncbi.nlm.nih.gov/pubmed/36587766
http://dx.doi.org/10.1016/j.jbc.2022.102849

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