Unraveling the impact of a germline heterozygous POLD1 frameshift variant in serrated polyposis syndrome

Serrated polyposis syndrome (SPS) is one of the most frequent polyposis syndromes characterized by an increased risk for developing colorectal cancer (CRC). Although SPS etiology has been mainly associated with environmental factors, germline predisposition to SPS could also be relevant for cases wi...

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Detalles Bibliográficos
Autores principales: Bonjoch, Laia, Soares de Lima, Yasmin, Díaz-Gay, Marcos, Dotti, Isabella, Muñoz, Jenifer, Moreira, Leticia, Carballal, Sabela, Ocaña, Teresa, Cuatrecasas, Miriam, Ortiz, Oswaldo, Castells, Antoni, Pellisé, Maria, Balaguer, Francesc, Salas, Azucena, Alexandrov, Ludmil B., Castellví-Bel, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900627/
https://www.ncbi.nlm.nih.gov/pubmed/36756361
http://dx.doi.org/10.3389/fmolb.2023.1119900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900627/
https://www.ncbi.nlm.nih.gov/pubmed/36756361
http://dx.doi.org/10.3389/fmolb.2023.1119900

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