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Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis

BACKGROUND AND OBJECTIVE: PCOS is a common metabolic disorder in women of reproductive age, which pathogenesis is very complex. The role of ferroptosis in PCOS is a novel finding, and the mechanistic studies are not clear. Metformin is a commonly used drug of PCOS but few studies on whether metformi...

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Detalles Bibliográficos
Autores principales: Peng, Qingjie, Chen, Xiaojiang, Liang, Xiaoxia, Ouyang, Jiahui, Wang, Qiangqiang, Ren, Shuai, Xie, Haibo, Wang, Chunhong, Sun, Yaqun, Wu, Xin, Liu, Hetao, Hei, Changchun, Sun, Miao, Chang, Qing, Liu, Xinrui, Li, Guangyong, He, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900736/
https://www.ncbi.nlm.nih.gov/pubmed/36755918
http://dx.doi.org/10.3389/fendo.2023.1070264