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Assessing HLA imputation accuracy in a West African population

The Human Leukocyte Antigen (HLA) region plays an important role in autoimmune and infectious diseases. HLA is a highly polymorphic region and thus difficult to impute. We therefore sought to evaluate HLA imputation accuracy, specifically in a West African population, since they are understudied and...

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Detalles Bibliográficos
Autores principales: Nanjala, Ruth, Mbiyavanga, Mamana, Hashim, Suhaila, de Villiers, Santie, Mulder, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900754/
https://www.ncbi.nlm.nih.gov/pubmed/36747714
http://dx.doi.org/10.1101/2023.01.23.525129