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RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection

Innate immune signaling in the central nervous system (CNS) exhibits many remarkable specializations that vary across cell types and CNS regions. In the setting of neuroinvasive flavivirus infection, neurons employ the immunologic kinase receptor-interacting kinase 3 (RIPK3) to promote an antiviral...

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Detalles Bibliográficos
Autores principales: Lindman, Marissa, Angel, Juan P, Estevez, Irving, Chang, Nydia P, Chou, Tsui-Wen, McCourt, Micheal, Atkins, Colm, Daniels, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900788/
https://www.ncbi.nlm.nih.gov/pubmed/36747672
http://dx.doi.org/10.1101/2023.01.23.525284