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scTOP: physics-inspired order parameters for cellular identification and visualization

Advances in single-cell RNA-sequencing (scRNA-seq) provide an unprecedented window into cellular identity. The increasing abundance of data requires new theoretical and computational frameworks for understanding cell fate determination, accurately classifying cell fates from expression data, and int...

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Detalles Bibliográficos
Autores principales: Yampolskaya, Maria, Herriges, Michael, Ikonomou, Laertis, Kotton, Darrell, Mehta, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900792/
https://www.ncbi.nlm.nih.gov/pubmed/36747864
http://dx.doi.org/10.1101/2023.01.25.525581