Ndel1 modulates dynein activation in two distinct ways

Dynein is the primary minus-end-directed microtubule motor [1]. To achieve activation, dynein binds to the dynactin complex and an adaptor to form the “activated dynein complex” [2, 3]. The protein Lis1 aids activation by binding to dynein and promoting its association with dynactin and adaptor [4,...

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Detalles Bibliográficos
Autores principales: Garrott, Sharon R, Gillies, John P, Siva, Aravintha, Little, Saffron R, Jbeily, Rita EI, DeSantis, Morgan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900795/
https://www.ncbi.nlm.nih.gov/pubmed/36747695
http://dx.doi.org/10.1101/2023.01.25.525437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900795/
https://www.ncbi.nlm.nih.gov/pubmed/36747695
http://dx.doi.org/10.1101/2023.01.25.525437

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