Time resolution in cryo-EM using a novel PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling

The rapid kinetics of biological processes and associated short-lived conformational changes pose a significant challenge in attempts to structurally visualize biomolecules during a reaction in real time. Conventionally, on-pathway intermediates have been trapped using chemical modifications or redu...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Sayan, Feng, Xiangsong, Maji, Suvrajit, Dadhwal, Prikshat, Zhang, Zhening, Brown, Zuben P., Frank, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900803/
https://www.ncbi.nlm.nih.gov/pubmed/36747778
http://dx.doi.org/10.1101/2023.01.25.525430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900803/
https://www.ncbi.nlm.nih.gov/pubmed/36747778
http://dx.doi.org/10.1101/2023.01.25.525430

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