Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness

The cumulative effects of T cell receptor (TCR) signal transduction over extended periods of time influences T cell biology, such as the positive selection of immature thymocytes or the proliferative responses of naive T cells. Naive T cells experience recurrent TCR signaling in response to self-ant...

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Detalles Bibliográficos
Autores principales: Eggert, Joel, Zinzow-Kramer, Wendy M., Hu, Yuesong, Tsai, Yuan-Li, Weiss, Arthur, Salaita, Khalid, Scharer, Christopher D., Au-Yeung, Byron B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900884/
https://www.ncbi.nlm.nih.gov/pubmed/36747815
http://dx.doi.org/10.1101/2023.01.27.525946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900884/
https://www.ncbi.nlm.nih.gov/pubmed/36747815
http://dx.doi.org/10.1101/2023.01.27.525946

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