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Deep learning enables fast, gentle STED microscopy

STED microscopy is widely used to image subcellular structures with super-resolution. Here, we report that denoising STED images with deep learning can mitigate photobleaching and photodamage by reducing the pixel dwell time by one or two orders of magnitude. Our method allows for efficient and robu...

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Detalles Bibliográficos
Autores principales: Ebrahimi, Vahid, Stephan, Till, Kim, Jiah, Carravilla, Pablo, Eggeling, Christian, Jakobs, Stefan, Han, Kyu Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900922/
https://www.ncbi.nlm.nih.gov/pubmed/36747618
http://dx.doi.org/10.1101/2023.01.26.525571