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Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13

Mycobacterium tuberculosis is currently the leading cause of death by any bacterial infection(1). The mycolic acid layer of the cell wall is essential for viability and virulence, and the enzymes responsible for its synthesis are therefore front line targets for antimycobacterial drug development(2,...

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Detalles Bibliográficos
Autores principales: Kim, Sun Kyung, Dickinson, Miles Sasha, Finer-Moore, Janet, Guan, Ziqiang, Kaake, Robyn M., Echeverria, Ignacia, Chen, Jen, Pulido, Ernst H., Sali, Andrej, Krogan, Nevan J., Rosenberg, Oren S., Stroud, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900942/
https://www.ncbi.nlm.nih.gov/pubmed/36747776
http://dx.doi.org/10.1101/2023.01.27.525930