Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches

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Rapid and accurate translation is essential in all organisms to produce properly folded and functional proteins. mRNA codons that define the protein coding sequences are decoded by tRNAs on the ribosome in the aminoacyl (A) binding site. The mRNA codon and the tRNA anticodon interaction is extensive...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha An, Hoffer, Eric D., Fagan, Crystal E., Maehigashi, Tatsuya, Dunham, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900946/
https://www.ncbi.nlm.nih.gov/pubmed/36747737
http://dx.doi.org/10.1101/2023.01.28.526049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900946/
https://www.ncbi.nlm.nih.gov/pubmed/36747737
http://dx.doi.org/10.1101/2023.01.28.526049

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