Cargando…

Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches

Mostrar otras versiones (1)

Rapid and accurate translation is essential in all organisms to produce properly folded and functional proteins. mRNA codons that define the protein coding sequences are decoded by tRNAs on the ribosome in the aminoacyl (A) binding site. The mRNA codon and the tRNA anticodon interaction is extensive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Ha An, Hoffer, Eric D., Fagan, Crystal E., Maehigashi, Tatsuya, Dunham, Christine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900946/ https://www.ncbi.nlm.nih.gov/pubmed/36747737 http://dx.doi.org/10.1101/2023.01.28.526049

Ejemplares similares

Structural basis for reduced ribosomal A-site fidelity in response to P-site codon–anticodon mismatches
por: Nguyen, Ha An, et al.
Publicado: (2023)

Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon–anticodon pairing
por: Hoffer, Eric D, et al.
Publicado: (2020)

Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding
por: Hoffer, Eric D, et al.
Publicado: (2019)

Molecular basis of ribosome recognition and mRNA hydrolysis by the E. coli YafQ toxin
por: Maehigashi, Tatsuya, et al.
Publicado: (2015)

The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix
por: Rozov, Alexey, et al.
Publicado: (2016)

Do anticodons of misacylated tRNAs preferentially mismatch codons coding for the misloaded amino acid?
por: Seligmann, Hervé
Publicado: (2010)

Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome
por: Washington, Arren Z., et al.
Publicado: (2014)

Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions
por: Hoernes, Thomas Philipp, et al.
Publicado: (2018)

Structural insights into translational recoding by frameshift suppressor tRNA(SufJ)
por: Fagan, Crystal E., et al.
Publicado: (2014)

A Major Controversy in Codon-Anticodon Adaptation Resolved by a New Codon Usage Index
por: Xia, Xuhua
Publicado: (2015)

How mutations in tRNA distant from the anticodon affect the fidelity of decoding
por: Schmeing, T. Martin, et al.
Publicado: (2011)

Factors That Shape Eukaryotic tRNAomes: Processing, Modification and Anticodon–Codon Use
por: Maraia, Richard J., et al.
Publicado: (2017)

Decoding system for the AUA codon by tRNA(Ile) with the UAU anticodon in Mycoplasma mobile
por: Taniguchi, Takaaki, et al.
Publicado: (2013)

Effects of tRNA modification on translational accuracy depend on intrinsic codon–anticodon strength
por: Manickam, Nandini, et al.
Publicado: (2016)

Base-Pairing Versatility Determines Wobble Sites in tRNA Anticodons of Vertebrate Mitogenomes
por: Fonseca, Miguel M., et al.
Publicado: (2012)

ACEing premature codon termination using anticodon-engineered sup-tRNA-based therapy
por: Lin, Ting-Yu, et al.
Publicado: (2022)

Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability
por: Pavelich, Ian J, et al.
Publicado: (2019)

Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection
por: Manjunath, Hema, et al.
Publicado: (2019)

Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution
por: Gelsinger, Diego Rivera, et al.
Publicado: (2020)

Variance in translational fidelity of different bacterial species is affected by pseudouridines in the tRNA anticodon stem-loop
por: Jürgenstein, Karl, et al.
Publicado: (2022)

Human SAMD9 is a poxvirus-activatable anticodon nuclease inhibiting codon-specific protein synthesis
por: Zhang, Fushun, et al.
Publicado: (2023)

Independent suppression of ribosomal +1 frameshifts by different tRNA anticodon loop modifications
por: Klassen, Roland, et al.
Publicado: (2016)

Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome
por: Belousoff, Matthew J., et al.
Publicado: (2017)

Codon-specific effects of tRNA anticodon loop modifications on translational misreading errors in the yeast Saccharomyces cerevisiae
por: Joshi, Kartikeya, et al.
Publicado: (2018)

Efficient engineering of chromosomal ribosome binding site libraries in mismatch repair proficient Escherichia coli
por: Oesterle, Sabine, et al.
Publicado: (2017)

Anticodon table of the chloroplast genome and identification of putative quadruplet anticodons in chloroplast tRNAs
por: Mohanta, Tapan Kumar, et al.
Publicado: (2023)

Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli
por: Singh, Sudhir, et al.
Publicado: (2023)

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo
por: Aron, Zachary D., et al.
Publicado: (2021)

The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias
por: Fabbretti, Attilio, et al.
Publicado: (2012)

Expression of a coronavirus ribosomal frameshift signal in Escherichia coli: influence of tRNA anticodon modification on frameshifting
por: Brierley, Ian, et al.
Publicado: (1997)

The Effect of Codon Mismatch on the Protein Translation System
por: Zhang, Dinglin, et al.
Publicado: (2016)

On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
por: Shigeoka, Toshiaki, et al.
Publicado: (2019)

A central fragment of ribosomal protein S26 containing the eukaryote-specific motif YxxPKxYxK is a key component of the ribosomal binding site of mRNA region 5′ of the E site codon
por: Sharifulin, Dmitri, et al.
Publicado: (2012)

The P-Site Loop of the Universally Conserved Bacterial Ribosomal Protein L5 Is Required for Maintaining Both Translation Rate and Fidelity
por: Bubunenko, Mikhail G., et al.
Publicado: (2023)

Chromatographic analysis of the aminoacyl-trnas which are required for translation of codons at and around the ribosomal frameshift sites of HIV, HTLV-1, and BLV
por: Hatfield, Dolph, et al.
Publicado: (1989)

The structure of the human tRNA(Lys3) anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairs
por: Bilbille, Yann, et al.
Publicado: (2009)

tRNA anticodon shifts in eukaryotic genomes
por: Rogers, Hubert H., et al.
Publicado: (2014)

Diel movement of brown trout, Salmo trutta, is reduced in dense populations with high site fidelity
por: Slavík, Ondřej, et al.
Publicado: (2018)

mRNA bound to the 30S subunit is a HigB toxin substrate
por: Schureck, Marc A., et al.
Publicado: (2016)

Atomic mutagenesis at the ribosomal decoding site
por: Schrode, Pius, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7pbgh6rmngo4qmpbkpdmc6nnkq