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Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy

Altered expression of vacuole membrane protein 1 (VMP1) has recently been observed in the context of multiple sclerosis and Parkinson’s disease (PD). However, how changes in VMP1 expression may impact pathogenesis has not been explored. Here, we report that genetic deletion of VMP1 from a monocytic...

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Detalles Bibliográficos
Autores principales: Zack, Stephanie R., Nikolaienko, Roman, Cook, Ben, Melki, Ronald, Zima, Aleksey V., Campbell, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900977/
https://www.ncbi.nlm.nih.gov/pubmed/36747822
http://dx.doi.org/10.21203/rs.3.rs-2508369/v1