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Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis

Inflammation and tissue fibrosis co-exist and are causally linked to organ dysfunction. However, the molecular mechanisms driving immune-fibroblast crosstalk in human cardiac disease remains unexplored and there are currently no therapeutics to target fibrosis. Here, we performed multi-omic single-c...

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Detalles Bibliográficos
Autores principales: Amrute, Junedh M., Luo, Xin, Penna, Vinay, Bredemeyer, Andrea, Yamawaki, Tracy, Yang, Steven, Kadyrov, Farid, Heo, Gyu-Seong, Shi, Sally Yu, Lee, Paul, Koenig, Andrew L., Kuppe, Christoph, Jones, Cameran, Kopecky, Benjamin, Hayat, Sikander, Ma, Pan, Terada, Yuriko, Fu, Angela, Furtado, Milena, Kreisel, Daniel, Stitziel, Nathan O., Li, Chi-Ming, Kramann, Rafael, Liu, Yongjian, Ason, Brandon, Lavine, Kory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900986/
https://www.ncbi.nlm.nih.gov/pubmed/36747878
http://dx.doi.org/10.21203/rs.3.rs-2402606/v1