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Aspergillus fumigatus transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection

Hyphal growth is essential for host colonization during Aspergillus infection. The transcription factor ZfpA regulates A. fumigatus hyphal development including branching, septation, and cell wall composition. However, how ZfpA affects fungal growth and susceptibility to host immunity during infecti...

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Detalles Bibliográficos
Autores principales: Schoen, Taylor J., Calise, Dante G., Bok, Jin Woo, Nwagwu, Chibueze D., Zarnowski, Robert, Andes, David, Huttenlocher, Anna, Keller, Nancy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901008/
https://www.ncbi.nlm.nih.gov/pubmed/36747761
http://dx.doi.org/10.1101/2023.01.25.525624