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RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice

Neurodevelopmental disorders (NDDs) are frequently associated with dendritic abnormalities in pyramidal neurons that affect arbor complexity, spine density, and synaptic communication (1,2). The underlying genetic causes are often complex, obscuring the molecular pathways that drive these disorders...

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Detalles Bibliográficos
Autores principales: Villar-Pazos, Sabrina, Thomas, Laurel, Yang, Yunhan, Chen, Kun, Lyles, Jenea B., Deitch, Bradley J., Ochaba, Joseph, Ling, Karen, Powers, Berit, Gingras, Sebastien, Kordasiewicz, Holly B., Grubisha, Melanie J., Huang, Yanhua H., Thomas, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901029/
https://www.ncbi.nlm.nih.gov/pubmed/36747781
http://dx.doi.org/10.21203/rs.3.rs-2440581/v1