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RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice
Neurodevelopmental disorders (NDDs) are frequently associated with dendritic abnormalities in pyramidal neurons that affect arbor complexity, spine density, and synaptic communication (1,2). The underlying genetic causes are often complex, obscuring the molecular pathways that drive these disorders...
Autores principales: | Villar-Pazos, Sabrina, Thomas, Laurel, Yang, Yunhan, Chen, Kun, Lyles, Jenea B., Deitch, Bradley J., Ochaba, Joseph, Ling, Karen, Powers, Berit, Gingras, Sebastien, Kordasiewicz, Holly B., Grubisha, Melanie J., Huang, Yanhua H., Thomas, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901029/ https://www.ncbi.nlm.nih.gov/pubmed/36747781 http://dx.doi.org/10.21203/rs.3.rs-2440581/v1 |
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