Harnessing Transcriptomic Signals for Amyotrophic Lateral Sclerosis to Identify Novel Drugs and Enhance Risk Prediction

INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. This study integrates the latest ALS genome-wide association study (GWAS) summary statistics with functional genomic annotations with the aim of providing mechanistic insights into ALS risk loci, inferring drug r...

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Detalles Bibliográficos
Autores principales: Pain, Oliver, Jones, Ashley, Al Khleifat, Ahmad, Agarwal, Devika, Hramyka, Dzmitry, Karoui, Hajer, Kubica, Jędrzej, Llewellyn, David J., Ranson, Janice M., Yao, Zhi, Iacoangeli, Alfredo, Al-Chalabi, Ammar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901068/
https://www.ncbi.nlm.nih.gov/pubmed/36747854
http://dx.doi.org/10.1101/2023.01.18.23284589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901068/
https://www.ncbi.nlm.nih.gov/pubmed/36747854
http://dx.doi.org/10.1101/2023.01.18.23284589

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