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HNRNPL induced circFAM13B increased bladder cancer immunotherapy sensitivity via inhibiting glycolysis through IGF2BP1/PKM2 pathway

BACKGROUND: The response rate to immunotherapy in patients with bladder cancer (BCa) remains relatively low. Considering the stable existence and important functions in tumour metabolism, the role of circRNAs in regulating immune escape and immunotherapy sensitivity is receiving increasing attention...

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Detalles Bibliográficos
Autores principales: Lv, Jiancheng, Li, Kai, Yu, Hao, Han, Jie, Zhuang, Juntao, Yu, Ruixi, Cheng, Yidong, Song, Qiang, Bai, Kexin, Cao, Qiang, Yang, Haiwei, Yang, Xiao, Lu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901087/
https://www.ncbi.nlm.nih.gov/pubmed/36747239
http://dx.doi.org/10.1186/s13046-023-02614-3