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New tools to study the interaction between integrins and latent TGFβ1

Transforming growth factor beta (TGFβ) 1 regulates cell differentiation and proliferation in different physiological settings, but is also involved in fibrotic progression and protects tumors from the immune system. Integrin αVβ6 has been shown to activate latent TGFβ1 by applying mechanical forces...

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Detalles Bibliográficos
Autores principales: Bachmann, Michael, Kessler, Jérémy, Burri, Elisa, Wehrle-Haller, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901185/
https://www.ncbi.nlm.nih.gov/pubmed/36747767
http://dx.doi.org/10.1101/2023.01.26.525682