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N-arylpyrazole NOD2 agonists promote immune checkpoint inhibitor therapy
The characterization of microbiota mechanisms in health and disease has reinvigorated pattern recognition receptors as prominent targets for immunotherapy. Notably, our recent studies on Enterococcus species revealed peptidoglycan remodeling and activation of NOD2 as key mechanisms for microbiota en...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901186/ https://www.ncbi.nlm.nih.gov/pubmed/36747725 http://dx.doi.org/10.1101/2023.01.26.525573 |