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N-arylpyrazole NOD2 agonists promote immune checkpoint inhibitor therapy

The characterization of microbiota mechanisms in health and disease has reinvigorated pattern recognition receptors as prominent targets for immunotherapy. Notably, our recent studies on Enterococcus species revealed peptidoglycan remodeling and activation of NOD2 as key mechanisms for microbiota en...

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Detalles Bibliográficos
Autores principales: Griffin, Matthew E., Tsukidate, Taku, Hang, Howard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901186/
https://www.ncbi.nlm.nih.gov/pubmed/36747725
http://dx.doi.org/10.1101/2023.01.26.525573