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β2-microglobulin alters the profiles of inflammatory cytokines and of matrix metalloprotease in macrophages derived from the osteoarthritic synovium

Several studies have implicated β2-microglobulin (B2M) in osteoarthritis (OA) pathology. Of the main constituents of synovial tissue, synovial fibroblasts and macrophages, the latter play a pivotal role in inflammation. Although several studies have investigated the effects of B2M on synovial fibrob...

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Detalles Bibliográficos
Autores principales: Muneshige, Kyoko, Uchida, Kentaro, Aikawa, Jun, Iwase, Dai, Takano, Shotaro, Miyagi, Masayuki, Inoue, Gen, Takaso, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901252/
https://www.ncbi.nlm.nih.gov/pubmed/36817398
http://dx.doi.org/10.5114/ceji.2022.124092