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Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4(+) T cells

The T-box transcription factors T-bet and Eomesodermin regulate type 1 immune responses in innate and adaptive lymphocytes. T-bet is widely expressed in the immune system but was initially identified as the lineage-specifying transcription factor of Th1 CD4(+) T cells, where it governs expression of...

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Detalles Bibliográficos
Autores principales: Thelen, Benedikt, Schipperges, Vincent, Knörlein, Paulina, Hummel, Jonas F., Arnold, Frederic, Kupferschmid, Laurence, Klose, Christoph S. N., Arnold, Sebastian J., Boerries, Melanie, Tanriver, Yakup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901365/
https://www.ncbi.nlm.nih.gov/pubmed/36756120
http://dx.doi.org/10.3389/fimmu.2023.1058267