Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules

Serpins are widely distributed and functionally diverse inhibitors of serine proteases. Ticks secrete serpins with anti-coagulation, anti-inflammatory, and immunomodulatory activities via their saliva into the feeding cavity to modulate host’s hemostatic and immune reaction initiated by the insertio...

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Detalles Bibliográficos
Autores principales: Chlastáková, Adéla, Kaščáková, Barbora, Kotál, Jan, Langhansová, Helena, Kotsyfakis, Michail, Kutá Smatanová, Ivana, Tirloni, Lucas, Chmelař, Jindřich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901544/
https://www.ncbi.nlm.nih.gov/pubmed/36756125
http://dx.doi.org/10.3389/fimmu.2023.1116324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901544/
https://www.ncbi.nlm.nih.gov/pubmed/36756125
http://dx.doi.org/10.3389/fimmu.2023.1116324

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