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Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules
Serpins are widely distributed and functionally diverse inhibitors of serine proteases. Ticks secrete serpins with anti-coagulation, anti-inflammatory, and immunomodulatory activities via their saliva into the feeding cavity to modulate host’s hemostatic and immune reaction initiated by the insertio...
Autores principales: | Chlastáková, Adéla, Kaščáková, Barbora, Kotál, Jan, Langhansová, Helena, Kotsyfakis, Michail, Kutá Smatanová, Ivana, Tirloni, Lucas, Chmelař, Jindřich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901544/ https://www.ncbi.nlm.nih.gov/pubmed/36756125 http://dx.doi.org/10.3389/fimmu.2023.1116324 |
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