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The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy

Immunotherapy has revolutionised cancer treatment. However, not all cancer patients benefit, and current stratification strategies based primarily on PD1 status and mutation burden are far from perfect. We hypothesised that high activation of an innate response relative to the adaptive response may...

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Detalles Bibliográficos
Autores principales: Ahrenfeldt, Johanne, Christensen, Ditte S., Østergaard, Andreas B., Kisistók, Judit, Sokač, Mateo, Birkbak, Nicolai J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901741/
https://www.ncbi.nlm.nih.gov/pubmed/36745657
http://dx.doi.org/10.1371/journal.pone.0281375