Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-derived 3D cardiac microtissues

Recent advances in human induced pluripotent stem cell (hiPSC)-derived cardiac microtissues provide a unique opportunity for cardiotoxic assessment of pharmaceutical and environmental compounds. Here, we developed a series of automated data processing algorithms to assess changes in action potential...

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Detalles Bibliográficos
Autores principales: Soepriatna, Arvin H., Navarrete-Welton, Allison, Kim, Tae Yun, Daley, Mark C., Bronk, Peter, Kofron, Celinda M., Mende, Ulrike, Coulombe, Kareen L. K., Choi, Bum-Rak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901774/
https://www.ncbi.nlm.nih.gov/pubmed/36745602
http://dx.doi.org/10.1371/journal.pone.0280406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901774/
https://www.ncbi.nlm.nih.gov/pubmed/36745602
http://dx.doi.org/10.1371/journal.pone.0280406

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