HDAC Inhibitors Alleviate Uric Acid–Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway

Uric acid (UA) accumulation triggers endothelial dysfunction, oxidative stress, and inflammation. Histone deacetylase (HDAC) plays a vital role in regulating the pathological processes of various diseases. However, the influence of HDAC inhibitor on UA-induced vascular endothelial cell injury (VECI)...

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Detalles Bibliográficos
Autores principales: Wang, Kaihao, Zhang, Youhong, Zhou, Min, Du, Yipeng, Li, Peixin, Guan, Chang, Huang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901848/
https://www.ncbi.nlm.nih.gov/pubmed/36607630
http://dx.doi.org/10.1097/FJC.0000000000001372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901848/
https://www.ncbi.nlm.nih.gov/pubmed/36607630
http://dx.doi.org/10.1097/FJC.0000000000001372

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