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HDAC Inhibitors Alleviate Uric Acid–Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway
Uric acid (UA) accumulation triggers endothelial dysfunction, oxidative stress, and inflammation. Histone deacetylase (HDAC) plays a vital role in regulating the pathological processes of various diseases. However, the influence of HDAC inhibitor on UA-induced vascular endothelial cell injury (VECI)...
Autores principales: | Wang, Kaihao, Zhang, Youhong, Zhou, Min, Du, Yipeng, Li, Peixin, Guan, Chang, Huang, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901848/ https://www.ncbi.nlm.nih.gov/pubmed/36607630 http://dx.doi.org/10.1097/FJC.0000000000001372 |
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