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Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling

Osteoarthritis (OA) is an age-related degenerative disease characterized by cartilage degeneration and abnormal bone remodeling in the subchondral bone. Autophagy maintains cellular homeostasis by self-phagocytosis. However, the underlying mechanisms of autophagy on the pathological progression of O...

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Detalles Bibliográficos
Autores principales: Yan, Jiangbo, Feng, Gangning, Yang, Yong, Ding, Dong, Ma, Long, Zhao, Xin, Chen, Xiaolei, Wang, Hui, Chen, Zhirong, Jin, Qunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901906/
https://www.ncbi.nlm.nih.gov/pubmed/35880352
http://dx.doi.org/10.17305/bjbms.2022.7677