The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling

High-throughput sequencing of adaptive immune receptor repertoires is a valuable tool for receiving insights in adaptive immunity studies. Several powerful TCR/BCR repertoire reconstruction and analysis methods have been developed in the past decade. However, detecting and correcting the discrepancy...

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Detalles Bibliográficos
Autores principales: Smirnova, Anastasia O, Miroshnichenkova, Anna M, Olshanskaya, Yulia V, Maschan, Michael A, Lebedev, Yuri B, Chudakov, Dmitriy M, Mamedov, Ilgar Z, Komkov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901932/
https://www.ncbi.nlm.nih.gov/pubmed/36692004
http://dx.doi.org/10.7554/eLife.69157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901932/
https://www.ncbi.nlm.nih.gov/pubmed/36692004
http://dx.doi.org/10.7554/eLife.69157

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