Pirfenidone Attenuates the EMT Process and the Secretion of VEGF in TGF-β2-Induced ARPE-19 Cells via Inhibiting the Activation of the NF-κB/Snail Signaling Pathway

AIM: Pirfenidone (PFD), an antifibrotic drug, has various beneficial functions such as antioxidant, antifibrotic, and anti-inflammatory effects. This study aimed to explore the molecular mechanisms underlying how PFD modulates retinal pigment epithelial (RPE) cells involved in neovascularization and...

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Detalles Bibliográficos
Autores principales: Li, Hongsong, Wang, Lijun, Shao, Meilin, Ren, Meimei, Zhang, Wenyi, Zhou, Jian, Wang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902120/
https://www.ncbi.nlm.nih.gov/pubmed/36756225
http://dx.doi.org/10.1155/2023/4798071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902120/
https://www.ncbi.nlm.nih.gov/pubmed/36756225
http://dx.doi.org/10.1155/2023/4798071

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