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Pirfenidone Attenuates the EMT Process and the Secretion of VEGF in TGF-β2-Induced ARPE-19 Cells via Inhibiting the Activation of the NF-κB/Snail Signaling Pathway

AIM: Pirfenidone (PFD), an antifibrotic drug, has various beneficial functions such as antioxidant, antifibrotic, and anti-inflammatory effects. This study aimed to explore the molecular mechanisms underlying how PFD modulates retinal pigment epithelial (RPE) cells involved in neovascularization and...

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Detalles Bibliográficos
Autores principales:	Li, Hongsong, Wang, Lijun, Shao, Meilin, Ren, Meimei, Zhang, Wenyi, Zhou, Jian, Wang, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902120/ https://www.ncbi.nlm.nih.gov/pubmed/36756225 http://dx.doi.org/10.1155/2023/4798071

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