GLX351322, a Novel NADPH Oxidase 4 Inhibitor, Attenuates TMJ Osteoarthritis by Inhibiting the ROS/MAPK/NF-κB Signaling Pathways

As a degenerative disease in joints, temporomandibular joint osteoarthritis (TMJOA) is characterized by progressive cartilage degradation, subchondral bone remodeling, and chronic synovitis, severely undermining functions and quality of life in patients. NADPH oxidase 4 (NOX4) contributes to reactiv...

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Detalles Bibliográficos
Autores principales: Zhen, Jinze, Chen, Xinwei, Mao, Yi, Xie, Xinru, Chen, Xuzhuo, Xu, Weifeng, Zhang, Shanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902131/
https://www.ncbi.nlm.nih.gov/pubmed/36756301
http://dx.doi.org/10.1155/2023/1952348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902131/
https://www.ncbi.nlm.nih.gov/pubmed/36756301
http://dx.doi.org/10.1155/2023/1952348

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