High-dose thiotepa, in conjunction with melphalan, followed by autologous hematopoietic stem cell transplantation in patients with pediatric solid tumors, including brain tumors

Among pediatric malignancies, solid tumors, particularly within the central nervous system (CNS), are common. Thiotepa, a myeloablative, high-dose chemotherapeutic (HDT) treatment administered prior to autologous hematopoietic stem cell transplantation (HSCT), can cross the blood-brain barrier and r...

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Detalles Bibliográficos
Autores principales: Hara, Junichi, Matsumoto, Kimikazu, Maeda, Naoko, Takahara-Matsubara, Mariko, Sugimoto, Saori, Goto, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902273/
https://www.ncbi.nlm.nih.gov/pubmed/36329150
http://dx.doi.org/10.1038/s41409-022-01820-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902273/
https://www.ncbi.nlm.nih.gov/pubmed/36329150
http://dx.doi.org/10.1038/s41409-022-01820-5

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