Reenacting Neuroectodermal Exposure of Hematopoietic Progenitors Enables Scalable Production of Cryopreservable iPSC-Derived Human Microglia

Human microglia, as innate immune cells of the central nervous system (CNS), play a central role in the pathogenesis of a large number of neurological and psychiatric disorders. However, experimental access to primary human microglia for biomedical applications such as disease modeling is extremely...

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Detalles Bibliográficos
Autores principales: Mathews, Mona, Wißfeld, Jannis, Flitsch, Lea Jessica, Shahraz, Anahita, Semkova, Vesselina, Breitkreuz, Yannik, Neumann, Harald, Brüstle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902330/
https://www.ncbi.nlm.nih.gov/pubmed/35971018
http://dx.doi.org/10.1007/s12015-022-10433-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902330/
https://www.ncbi.nlm.nih.gov/pubmed/35971018
http://dx.doi.org/10.1007/s12015-022-10433-w

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