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25-hydroxyvitamin D(3) generates immunomodulatory plasticity in human periodontal ligament-derived mesenchymal stromal cells that is inflammatory context-dependent

INTRODUCTION: Human periodontal ligament-derived mesenchymal stromal cells (hPDL-MSCs) exhibit a tight bi-directional interaction with CD4(+) T lymphocytes. The hPDL-MSCs’ immunomodulatory abilities are drastically enhanced by pro-inflammatory cytokines via boosting the expression of various immunom...

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Detalles Bibliográficos
Autores principales: Behm, Christian, Blufstein, Alice, Gahn, Johannes, Moritz, Andreas, Rausch-Fan, Xiaohui, Andrukhov, Oleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902380/
https://www.ncbi.nlm.nih.gov/pubmed/36761739
http://dx.doi.org/10.3389/fimmu.2023.1100041