Binding and functional structure-activity similarities of 4-substituted 2,5-dimethoxyphenyl isopropylamine analogues at 5-HT(2A) and 5-HT(2B) serotonin receptors

Certain 4-substituted analogs of 1-(2,5-dimethoxyphenyl)isopropylamine (2,5-DMA) are psychoactive classical hallucinogens or serotonergic psychedelic agents that function as human 5-HT(2A) (h5-HT(2A)) serotonin receptor agonists. Activation of a related receptor population, h5-HT(2B) receptors, has...

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Detalles Bibliográficos
Autores principales: Hemanth, Prithvi, Nistala, Pallavi, Nguyen, Vy T., Eltit, Jose M., Glennon, Richard A., Dukat, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902381/
https://www.ncbi.nlm.nih.gov/pubmed/36762110
http://dx.doi.org/10.3389/fphar.2023.1101290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902381/
https://www.ncbi.nlm.nih.gov/pubmed/36762110
http://dx.doi.org/10.3389/fphar.2023.1101290

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