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PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis

Stem cell senescence and depletion are major causes of aging and aging-related diseases. The NAD (Nicotinamide adenine dinucleotide) – SIRT1 (Silent Information Regulator 1) – PARP1 (Poly (ADP-ribose) polymerase-1) axis has gained interest owing to its significant role in regulating stem cell senesc...

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Detalles Bibliográficos
Autores principales: Wang, Yuan, Sui, Yutong, Niu, Ye, Liu, Dan, Xu, Qi, Liu, Feilin, Zuo, Kuiyang, Liu, Mingsheng, Sun, Wei, Wang, Ziyu, Liu, Zinan, Zou, Fei, Shi, Jiahong, Liu, Xiaomei, Liu, Jinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902417/
https://www.ncbi.nlm.nih.gov/pubmed/35962175
http://dx.doi.org/10.1007/s12015-022-10425-w