Cargando…

PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis

Stem cell senescence and depletion are major causes of aging and aging-related diseases. The NAD (Nicotinamide adenine dinucleotide) – SIRT1 (Silent Information Regulator 1) – PARP1 (Poly (ADP-ribose) polymerase-1) axis has gained interest owing to its significant role in regulating stem cell senesc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yuan, Sui, Yutong, Niu, Ye, Liu, Dan, Xu, Qi, Liu, Feilin, Zuo, Kuiyang, Liu, Mingsheng, Sun, Wei, Wang, Ziyu, Liu, Zinan, Zou, Fei, Shi, Jiahong, Liu, Xiaomei, Liu, Jinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902417/ https://www.ncbi.nlm.nih.gov/pubmed/35962175 http://dx.doi.org/10.1007/s12015-022-10425-w

Ejemplares similares

PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair
por: Wang, Yuan, et al.
Publicado: (2021)

NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling
por: Liu, Feilin, et al.
Publicado: (2019)

Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization
por: Liu, Mingsheng, et al.
Publicado: (2022)

Comprehensive overview of the role of PBX1 in mammalian kidneys
por: Zou, Fei, et al.
Publicado: (2023)

G-quadruplexes folding mediates downregulation of PBX1 expression in melanoma
por: Sui, Yutong, et al.
Publicado: (2023)

MSC-derived exosomes attenuate cell death through suppressing AIF nucleus translocation and enhance cutaneous wound healing
por: Zhao, Guifang, et al.
Publicado: (2020)

L-Ascorbic Acid 2-Phosphate Attenuates Methylmercury-Induced Apoptosis by Inhibiting Reactive Oxygen Species Accumulation and DNA Damage in Human SH-SY5Y Cells
por: Zuo, Kuiyang, et al.
Publicado: (2023)

CRISPR-Cas12a-based detection of monkeypox virus
por: Sui, Yutong, et al.
Publicado: (2022)

PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
por: Jiang, Yixu, et al.
Publicado: (2019)

Research progress of PBX1 in developmental and regenerative medicine
por: Chen, Hao, et al.
Publicado: (2023)

PBX1 is a valuable prognostic biomarker for patients with breast cancer
por: Ao, Xiang, et al.
Publicado: (2020)

Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites
por: Thiaville, Michelle M., et al.
Publicado: (2012)

FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression
por: Wang, Pan, et al.
Publicado: (2017)

Sirt1: Def-eating senescence?
por: Fusco, Salvatore, et al.
Publicado: (2012)

SIRT6 in Senescence and Aging-Related Cardiovascular Diseases
por: Li, Xiaokang, et al.
Publicado: (2021)

SIRT3 consolidates heterochromatin and counteracts senescence
por: Diao, Zhiqing, et al.
Publicado: (2021)

The Effect of High-Quality RDX on the Safety and Mechanical Properties of Pressed PBX
por: Chen, Shixiong, et al.
Publicado: (2022)

P2X1 enhances leukemogenesis through PBX3-BCAT1 pathways
por: He, Xiaoxiao, et al.
Publicado: (2022)

SIRT1 is downregulated by autophagy in senescence and aging
por: Xu, Caiyue, et al.
Publicado: (2020)

Paternal mosaicism for a novel PBX1 mutation associated with recurrent perinatal death: Phenotypic expansion of the PBX1‐related syndrome
por: Arts, Peer, et al.
Publicado: (2020)

PBX3 in Cancer
por: Morgan, Richard, et al.
Publicado: (2020)

SIRT1 upregulation promotes epithelial-mesenchymal transition by inducing senescence escape in endometriosis
por: Wang, Minghua, et al.
Publicado: (2022)

Correction to ‘SIRT3 consolidates heterochromatin and counteracts senescence’
por: Diao, Zhiqing, et al.
Publicado: (2021)

Avoiding lentiviral transduction culture induced MSC senescence
por: Pan, Yung-Wei, et al.
Publicado: (2009)

Recent Developed Strategies for Enhancing Chondrogenic Differentiation of MSC: Impact on MSC-Based Therapy for Cartilage Regeneration
por: Zha, Kangkang, et al.
Publicado: (2021)

Efficacy of 5-aminolevulinic acid–based photodynamic therapy against keloid compromised by downregulation of SIRT1-SIRT3-SOD2-mROS dependent autophagy pathway
por: Liu, Tao, et al.
Publicado: (2018)

Roflumilast Attenuates Doxorubicin-Induced Cardiotoxicity by Targeting Inflammation and Cellular Senescence in Cardiomyocytes Mediated by SIRT1
por: Zhang, Sheng, et al.
Publicado: (2021)

Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6
por: Liu, Rong, et al.
Publicado: (2014)

Inhibition of SIRT1 Limits Self-Renewal and Oncogenesis by Inducing Senescence of Liver Cancer Stem Cells
por: Wang, Min-Jun, et al.
Publicado: (2021)

SIRT1 is regulated by a PPARγ–SIRT1 negative feedback loop associated with senescence
por: Han, Limin, et al.
Publicado: (2010)

WWOX Modulates ROS-Dependent Senescence in Bladder Cancer
por: Liu, Ching-Wen, et al.
Publicado: (2022)

Polymorphism in the PBX1 gene is related to cystinuria in Brazilian families
por: Reis, Sabrina T., et al.
Publicado: (2018)

PBX1 as Pioneer Factor: A Case Still Open
por: Grebbin, Britta M., et al.
Publicado: (2017)

Ibrutinib is not an effective drug in primografts of TCF3-PBX1
por: van de Ven, Cesca, et al.
Publicado: (2020)

Tumorigenic Aspects of MSC Senescence—Implication in Cancer Development and Therapy
por: Mojsilović, Slavko, et al.
Publicado: (2021)

m(6)A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels
por: Liu, Yinan, et al.
Publicado: (2022)

High-affinity Na(+)-dependent dicarboxylate cotransporter promotes cellular senescence by inhibiting SIRT1
por: Liu, Weiping, et al.
Publicado: (2010)

A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma
por: He, Changyu, et al.
Publicado: (2017)

SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence
por: Wan, Yan-Zhen, et al.
Publicado: (2014)

Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis
por: Lim, Chae Jin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p8de1jcns4kp44dh10i59gh92u