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Activation of the STING pathway induces peripheral sensitization via neuroinflammation in a rat model of bone cancer pain

BACKGROUND: Neuroinflammation in the peripheral nervous system has been linked to cancer metastasis-induced bone pain. The stimulator of interferon genes (STING), an innate immune sensor for cytosolic DNA, plays an important role in inflammation and cancer metastasis and is reported to be a critical...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxin, Wang, Wei, Gong, Zhihao, Peng, Yuan, Li, Xin, Zhang, Zuojing, Zhang, Xiaoxuan, You, Xingji, Wu, Jingxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902424/
https://www.ncbi.nlm.nih.gov/pubmed/36346430
http://dx.doi.org/10.1007/s00011-022-01663-2