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Activation of the STING pathway induces peripheral sensitization via neuroinflammation in a rat model of bone cancer pain
BACKGROUND: Neuroinflammation in the peripheral nervous system has been linked to cancer metastasis-induced bone pain. The stimulator of interferon genes (STING), an innate immune sensor for cytosolic DNA, plays an important role in inflammation and cancer metastasis and is reported to be a critical...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902424/ https://www.ncbi.nlm.nih.gov/pubmed/36346430 http://dx.doi.org/10.1007/s00011-022-01663-2 |