Intratumoral heterogeneity affects tumor regression and Ki67 proliferation index in perioperatively treated gastric carcinoma

BACKGROUND: Intratumoral heterogeneity (ITH) is a major problem in gastric cancer (GC). We tested Ki67 and tumor regression for ITH after neoadjuvant/perioperative chemotherapy. METHODS: 429 paraffin blocks were obtained from 106 neoadjuvantly/perioperatively treated GCs (one to five blocks per case...

Descripción completa

Detalles Bibliográficos
Autores principales: Kock am Brink, Magnus, Dunst, Laura Sophie, Behrens, Hans-Michael, Krüger, Sandra, Becker, Thomas, Röcken, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902476/
https://www.ncbi.nlm.nih.gov/pubmed/36347963
http://dx.doi.org/10.1038/s41416-022-02047-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902476/
https://www.ncbi.nlm.nih.gov/pubmed/36347963
http://dx.doi.org/10.1038/s41416-022-02047-3

Ejemplares similares