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The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition

The intimate association between the endoplasmic reticulum (ER) and mitochondrial membranes at ER-Mitochondria contact sites (ERMCS) is a platform for critical cellular processes, particularly lipid synthesis. How contacts are remodeled and the impact of altered contacts on lipid metabolism remains...

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Detalles Bibliográficos
Autores principales: Ganji, Rakesh, Paulo, Joao A., Xi, Yuecheng, Kline, Ian, Zhu, Jiang, Clemen, Christoph S., Weihl, Conrad C., Purdy, John G., Gygi, Steve P., Raman, Malavika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902492/
https://www.ncbi.nlm.nih.gov/pubmed/36746962
http://dx.doi.org/10.1038/s41467-023-36298-2