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The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition
The intimate association between the endoplasmic reticulum (ER) and mitochondrial membranes at ER-Mitochondria contact sites (ERMCS) is a platform for critical cellular processes, particularly lipid synthesis. How contacts are remodeled and the impact of altered contacts on lipid metabolism remains...
Autores principales: | Ganji, Rakesh, Paulo, Joao A., Xi, Yuecheng, Kline, Ian, Zhu, Jiang, Clemen, Christoph S., Weihl, Conrad C., Purdy, John G., Gygi, Steve P., Raman, Malavika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902492/ https://www.ncbi.nlm.nih.gov/pubmed/36746962 http://dx.doi.org/10.1038/s41467-023-36298-2 |
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