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Denervation during mandibular distraction osteogenesis results in impaired bone formation

Mandibular distraction osteogenesis (DO) is mediated by skeletal stem cells (SSCs) in mice, which enact bone regeneration via neural crest re-activation. As peripheral nerves are essential to progenitor function during development and in response to injury, we questioned if denervation impairs mandi...

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Detalles Bibliográficos
Autores principales: Tevlin, Ruth, Griffin, Michelle, Chen, Kellen, Januszyk, Michael, Guardino, Nick, Spielman, Amanda, Walters, Shannon, Gold, Garry Evan, Chan, Charles K. F., Gurtner, Geoffrey C., Wan, Derrick C., Longaker, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902545/
https://www.ncbi.nlm.nih.gov/pubmed/36747028
http://dx.doi.org/10.1038/s41598-023-27921-9